Lithium Carbonate and Olanzapine: Interaction Overview

Lithium Carbonate (Lithobid) + Olanzapine (Zyprexa)

Severity: Moderate

FDA label language suggests this combination may require monitoring, dose adjustment, or added caution. Make sure every prescriber involved in your care knows you take both.

Basis: Drug interactions section — monitoring/caution language of the Olanzapine FDA label.

What the FDA Label Says

Therefore, concomitant olanzapine administration does not require dosage adjustment of lithium [see Warnings and Precautions ( 5.16 )] .

Excerpt from the FDA prescribing label for Olanzapine (SPL set ID 002dd00f-7946-ea4f-e063-6294a90a5916).

About These Medications

  • Lithium Carbonate (Lithobid) medication guide — Mood Stabilizer
  • Olanzapine (Zyprexa) medication guide — Atypical Antipsychotic

Check other combinations with our interaction tool →

About this interaction data. These interactions were identified by automatically scanning FDA prescribing-label text for medications in Bridgeway's library. This is not a complete list and is not a substitute for review by your prescriber or pharmacist, who use comprehensive clinical databases. Always share your full medication list with your care team. How we source this data →

One care team, one medication plan

Bridgeway's Utah prescribers coordinate medication management with therapy — so interactions like this one are reviewed by people who see your whole picture.

Request an Appointment Call (801) 255-5131

Not medical advice. This page summarizes publicly available FDA drug labeling alongside general guidance from Bridgeway Integrated Healthcare Services. It is for educational purposes only and is not a substitute for advice from your prescriber or pharmacist. Never start, stop, or change a medication without talking to your healthcare provider. In an emergency, call 911.