Buspirone Hydrochloride (Buspar) + Clomipramine Hydrochloride (Anafranil)
FDA label language suggests this combination may require monitoring, dose adjustment, or added caution. Make sure every prescriber involved in your care knows you take both.
Basis: Warnings section — monitoring/caution language of the Clomipramine Hydrochloride FDA label.
Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIs, including clomipramine hydrochloride capsules, USP alone but particularly with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St.
Excerpt from the FDA prescribing label for Clomipramine Hydrochloride (SPL set ID 0bbee292-0fba-4606-9c8e-4723742682c0).
About this interaction data. These interactions were identified by automatically scanning FDA prescribing-label text for medications in Bridgeway's library. This is not a complete list and is not a substitute for review by your prescriber or pharmacist, who use comprehensive clinical databases. Always share your full medication list with your care team. How we source this data →
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Request an Appointment Call (801) 255-5131Not medical advice. This page summarizes publicly available FDA drug labeling alongside general guidance from Bridgeway Integrated Healthcare Services. It is for educational purposes only and is not a substitute for advice from your prescriber or pharmacist. Never start, stop, or change a medication without talking to your healthcare provider. In an emergency, call 911.